Exposure or exposure means that, in the course of employment, an employee is exposed to a chemical that poses a physical or health hazard and involves potential exposure (e.g., accidental or potential). The “impaired” category for health hazards includes any route of entry (e.g., inhalation, ingestion, dermal contact, or absorption). A.5.1.3 This hazard class primarily concerns chemicals that can cause mutations in human germ cells that can be passed on to offspring. However, the classification of substances and mixtures to be reported in vivo shall also take into account in vitro and in vivo somatic cell mutagenicity/genotoxicity tests. (v) If an employer without a business account purchases a hazardous chemical product from a retailer that is not required to have safety data sheets on file (i.e., the retailer does not have a business account and does not use the materials), the retailer must provide the employer with the name, address and telephone number of the chemical manufacturer upon request. importer or distributor from whom a safety data sheet is available; The generation of income account is an arrangement whereby a retail distributor sells hazardous chemicals to an employer, usually in bulk over time and/or at a cost below the regular retail price. A.0.2.3 “Scientifically validated” means the method used to establish the reliability and suitability of a method for a particular purpose. Any hazardous properties test carried out in accordance with accepted scientific principles may be used to determine health hazards. Test conditions should be standardized so that results are reproducible with a particular substance and the standardized test provides “valid” data to define the hazard class of concern.

A.0.4.3.2. If the classification society has information indicating that the hazard of an ingredient below the specified concentration limit/limit is obvious (i.e. presents a health risk), the mixture containing that ingredient shall be classified accordingly. (vi) Pesticide treated agricultural or plant seed labeled in accordance with the federal seed law (7 U.S.C. 1551 et seq.) and the labeling requirements adopted by the Department of Agriculture under that Act. 1. The purpose of this section is to ensure that the hazards of all manufactured and imported chemicals are classified and that information on classified hazards is communicated to employers and workers. The requirements in this section are intended to be consistent with the provisions of Revision 3 of the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (GHS). Information will be communicated through comprehensive hazard communication programs that will include container labelling and other forms of warning, safety data sheets and employee training. Immediate use means that the hazardous chemical is controlled and used only by the person transferring it from a labelled container and only during the shift during which it is settled. (iv) Laboratory employers who ship hazardous chemicals shall be considered manufacturers or distributors of chemicals for the purposes of this Regulation and shall therefore ensure that all containers containing hazardous chemicals leaving the laboratory are labelled in accordance with point (f) of this Section and that a safety data sheet is made available to distributors and other employers in accordance with the points (g)(6) and (g)(7) of this Section. 8.

The employer is not required to label portable containers containing hazardous chemicals from labelled containers that are intended solely for the direct use of the transferring worker. For the purposes of this Section, medicinal products supplied by a pharmacy to a healthcare provider for direct administration to a patient shall be exempt from labelling. A.1.3.5.1. If the mixture itself has not been subjected to acute toxicity tests, but sufficient data are available on both the individual ingredients and similar mixtures tested to adequately characterize the hazards of the mixture, these data shall be used in accordance with the following bridging principles set out in section A.0.5 of this appendix: dilution, determination, concentration of mixtures, interpolation within a toxicity category, mixtures and aerosols substantially similar. A safety statement is a term that describes the recommended actions that should be taken to minimize or prevent harmful effects resulting from exposure to a hazardous chemical or improper storage or handling. (ix) Consumer Products or Hazardous Substances as defined in the Consumer Product Safety Act (15 U.S.C. 2051 et seq.) and the federal Hazardous Substances Act (15 U.S.C. 1261 et seq.) or if the employer can demonstrate that it is used in the workplace for the purpose intended by the chemical manufacturer or importer and that the use results in a duration and frequency of exposure not exceeding the range of exposure that consumers could reasonably experience when used for the intended purpose; Label: an appropriate group of written, printed or graphic information on a hazardous chemical affixed, printed or affixed to the immediate container of a hazardous chemical or any outer packaging. (iii) Retailers selling hazardous chemicals to employers who have a business account shall, upon request, provide those employers with a safety data sheet, affix a label or otherwise inform them that a safety data sheet is available. A worker is a worker who may be exposed to hazardous chemicals under normal operating conditions or in foreseeable emergency situations. Workers such as office workers or bank employees who encounter hazardous chemicals only in isolated and non-common cases are not covered. 5 It should be noted that the criteria for the classification of health hazards generally include a tiered system in which the available test data for the whole mixture are taken into account as the first step in the assessment, followed by the applicable bridging principles and, finally, limit values/concentration limits or additivity.

However, this approach is not used for germ cell mutagenicity. These germ cell mutagenicity criteria take into account the concentration limits/limits as the primary stage and allow for classification changes only on the basis of a case-by-case assessment based on available test data for the mixture as a whole. (ii) Employers shall retain all safety data sheets received with incoming shipments of hazardous chemicals and ensure that they are readily accessible to laboratory personnel during each shift while in their work area. A.0.4.3.1. When classifying an untested mixture on the basis of the hazards of its constituents, concentration limits/limits for classified ingredients of the mixture for more than one hazard class shall be used. Although the presumed limits/concentration limits adequately identify the hazard for most mixtures, some may contain hazardous ingredients at concentrations below the specified concentration limits or limits that still present an identifiable hazard. There may also be cases where the concentration limit/limit is significantly lower than the non-hazardous value set for an ingredient. A.3.3.3. The step-by-step approach explains how to organise existing information on a substance and, where appropriate, how to take a decision on the weight of evidence for hazard assessment and classification. A.1.3.6.2.3.

If an ingredient of unknown acute toxicity is used in a mixture at a concentration of ≥1 % and the mixture has not been classified on the basis of the examination of the mixture as a whole, no final acute toxicity estimate can be attributed to the mixture.